api where host.os.type == "windows" and 
  process.Ext.api.name in ("OpenProcess", "OpenThread") and Target.process.name : "lsass.exe" and 
  not 
  (
    process.executable : (
        "?:\\ProgramData\\GetSupportService*\\Updates\\Update_*.exe",
        "?:\\ProgramData\\Microsoft\\Windows Defender\\Platform\\*\\MsMpEng.exe",
        "?:\\Program Files (x86)\\Asiainfo Security\\OfficeScan Client\\NTRTScan.exe",
        "?:\\Program Files (x86)\\Blackpoint\\SnapAgent\\SnapAgent.exe",
        "?:\\Program Files (x86)\\CheckPoint\\Endpoint Security\\EFR\\EFRService.exe",
        "?:\\Program Files (x86)\\CyberCNSAgent\\osqueryi.exe",
        "?:\\Program Files (x86)\\cisco\\cisco anyconnect secure mobility client\\vpnagent.exe",
        "?:\\Program Files (x86)\\cisco\\cisco anyconnect secure mobility client\\aciseagent.exe",
        "?:\\Program Files (x86)\\cisco\\cisco anyconnect secure mobility client\\vpndownloader.exe",
        "?:\\Program Files (x86)\\eScan\\reload.exe",
        "?:\\Program Files (x86)\\Google\\Update\\GoogleUpdate.exe",
        "?:\\Program Files (x86)\\Kaspersky Lab\\*\\avp.exe",
        "?:\\Program Files (x86)\\microsoft intune management extension\\microsoft.management.services.intunewindowsagent.exe",
        "?:\\Program Files (x86)\\N-able Technologies\\Reactive\\bin\\NableReactiveManagement.exe",
        "?:\\Program Files (x86)\\N-able Technologies\\Windows Agent\\bin\\agent.exe",
        "?:\\Program Files (x86)\\Tanium\\Tanium Client\\TaniumClient.exe",
        "?:\\Program Files (x86)\\Trend Micro\\*\\CCSF\\TmCCSF.exe",
        "?:\\Program Files (x86)\\Trend Micro\\Security Agent\\TMASutility.exe",
        "?:\\Program Files*\\Windows Defender\\MsMpEng.exe",
        "?:\\Program Files\\Bitdefender\\Endpoint Security\\EPSecurityService.exe",
        "?:\\Program Files\\Cisco\\AMP\\*\\sfc.exe",
        "?:\\Program Files\\Common Files\\McAfee\\AVSolution\\mcshield.exe",
        "?:\\Program Files\\EA\\AC\\EAAntiCheat.GameService.exe",
        "?:\\Program Files\\Elastic\\Agent\\data\\elastic-agent-*\\components\\agentbeat.exe",
        "?:\\Program Files\\Elastic\\Agent\\data\\elastic-agent-*\\components\\metricbeat.exe",
        "?:\\Program Files\\Elastic\\Agent\\data\\elastic-agent-*\\components\\osqueryd.exe",
        "?:\\Program Files\\Elastic\\Agent\\data\\elastic-agent-*\\components\\packetbeat.exe",
        "?:\\Program Files\\ESET\\ESET Security\\ekrn.exe",
        "?:\\Program Files\\Fortinet\\FortiClient\\FortiProxy.exe",
        "?:\\Program Files\\Fortinet\\FortiClient\\FortiSSLVPNdaemon.exe",
        "?:\\Program Files\\Goverlan Inc\\GoverlanAgent\\GovAgentx64.exe",
        "?:\\Program Files\\Huntress\\HuntressAgent.exe",
        "?:\\Program Files\\LogicMonitor\\Agent\\bin\\sbshutdown.exe",
        "?:\\Program Files\\Malwarebytes\\Anti-Malware\\MBAMService.exe",
        "?:\\Program Files\\Microsoft Monitoring Agent\\Agent\\Health Service State\\*\\pmfexe.exe", 
        "?:\\Program Files\\Microsoft Security Client\\MsMpEng.exe",
        "?:\\Program Files\\Qualys\\QualysAgent\\QualysAgent.exe",
        "?:\\Program Files\\smart-x\\controlupagent\\version*\\cuagent.exe",
        "?:\\Program Files\\TDAgent\\ossec-agent\\ossec-agent.exe",
        "?:\\Program Files\\Topaz OFD\\Warsaw\\core.exe",
        "?:\\Program Files\\Trend Micro\\Deep Security Agent\\netagent\\tm_netagent.exe",
        "?:\\Program Files\\VMware\\VMware Tools\\vmtoolsd.exe",
        "?:\\Program Files\\Windows Defender Advanced Threat Protection\\MsSense.exe",
        "?:\\Program Files\\Wise\\Wise Memory Optimizer\\WiseMemoryOptimzer.exe",
        "?:\\Windows\\AdminArsenal\\PDQDeployRunner\\*\\exec\\Sysmon64.exe",
        "?:\\Windows\\Sysmon.exe",
        "?:\\Windows\\Sysmon64.exe",
        "?:\\Windows\\System32\\csrss.exe",
        "?:\\Windows\\System32\\MRT.exe",
        "?:\\Windows\\System32\\msiexec.exe",
        "?:\\Windows\\System32\\taskhostw.exe",
        "?:\\Windows\\System32\\RtkAudUService64.exe",
        "?:\\Windows\\System32\\wbem\\WmiPrvSE.exe",
        "?:\\Windows\\SysWOW64\\wbem\\WmiPrvSE.exe",
        "?:\\Windows\\tenable_mw_scan_142a90001fb65e0beb1751cc8c63edd0.exe"
    ) and not ?process.code_signature.trusted == false
  )