event.category: "process" and host.os.type:windows and
(
  powershell.file.script_block_text: "Set-MpPreference" and
  powershell.file.script_block_text: (
    DisableArchiveScanning or DisableBehaviorMonitoring or
    DisableIntrusionPreventionSystem or DisableIOAVProtection or
    DisableRemovableDriveScanning or DisableBlockAtFirstSeen or
    DisableScanningMappedNetworkDrivesForFullScan or
    DisableScanningNetworkFiles or DisableScriptScanning or
    DisableRealtimeMonitoring or LowThreatDefaultAction or
    ModerateThreatDefaultAction or HighThreatDefaultAction
  )
) and
not powershell.file.script_block_text : (
  ("cmdletization" and "cdxml-Help.xml") or
  ("function Set-MpPreference" and "Microsoft.PowerShell.Cmdletization.GeneratedTypes.MpPreference.SubmitSamplesConsentType")
) and
not file.directory : "C:\ProgramData\Microsoft\Windows Defender Advanced Threat Protection\SenseCM" and
not user.id : "S-1-5-18"