event.category:process and host.os.type:windows and
  powershell.file.script_block_text:(
    "Invoke-TokenManipulation" or
    "ImpersonateNamedPipeClient" or
    "NtImpersonateThread" or
    (
      "STARTUPINFOEX" and
      "UpdateProcThreadAttribute"
    ) or
    (
      "AdjustTokenPrivileges" and
      "SeDebugPrivilege"
    ) or
    (
      ("DuplicateToken" or
      "DuplicateTokenEx") and
      ("SetThreadToken" or
      "ImpersonateLoggedOnUser" or
      "CreateProcessWithTokenW" or
      "CreatePRocessAsUserW" or
      "CreateProcessAsUserA")
    ) 
  ) and
  not (
    user.id:("S-1-5-18" or "S-1-5-19" or "S-1-5-20") and
    file.directory: "C:\\ProgramData\\Microsoft\\Windows Defender Advanced Threat Protection\\Downloads"
  ) and
  not powershell.file.script_block_text : (
    "sentinelbreakpoints" and "Set-PSBreakpoint" and "PowerSploitIndicators"
  ) and
  not (
    powershell.file.script_block_text : "New-HPPrivateToastNotificationLogo" and
    file.path : "C:\Program Files\HPConnect\hp-cmsl-wl\modules\HP.Notifications\HP.Notifications.psm1"
  )